Early Detection Saves Lives: The Importance of Screening for Ovarian and Uterine Cancer


Ovarian and uterine cancers are among the leading causes of cancer-related deaths in women worldwide. However, these cancers are often diagnosed at advanced stages when treatment options are limited and prognosis is poor. Say’s Dr Scott Kamelle,  early detection through screening plays a pivotal role in improving survival rates and reducing mortality from these malignancies. In this article, we explore the importance of screening for ovarian and uterine cancer, highlighting the benefits of early intervention in saving lives.

The Need for Screening

Silent Diseases: Ovarian and uterine cancers are often referred to as “silent killers” due to their propensity to cause subtle or nonspecific symptoms in the early stages. Many women may not experience noticeable signs until the disease has progressed to an advanced stage, making early detection challenging.

High Mortality Rates: Both ovarian and uterine cancers have high mortality rates, particularly when diagnosed at later stages. Delayed diagnosis contributes to poorer treatment outcomes, increased treatment-related morbidity, and reduced overall survival rates for affected individuals.

Screening Modalities

Transvaginal Ultrasound: Transvaginal ultrasound is a non-invasive imaging technique used to visualize the ovaries and uterus. This screening method can detect abnormal masses or lesions that may indicate the presence of ovarian or uterine cancer, facilitating early diagnosis and intervention.

CA-125 Blood Test: The CA-125 blood test measures the levels of a protein called CA-125 in the blood, which may be elevated in individuals with ovarian cancer. While not specific to ovarian cancer, an elevated CA-125 level may prompt further diagnostic evaluation, including imaging studies and biopsy.

Symptoms and Risk Factors

Common Symptoms: Recognizing the signs and symptoms of ovarian and uterine cancer is crucial for early detection. Symptoms may include abdominal bloating, pelvic pain or pressure, changes in bowel or bladder habits, abnormal vaginal bleeding, and unexplained weight loss. Women experiencing persistent or unusual symptoms should promptly seek medical evaluation.

Risk Factors: Certain factors increase the risk of developing ovarian and uterine cancer, including advancing age, family history of gynecologic cancers, inherited genetic mutations (such as BRCA1 and BRCA2), obesity, hormonal imbalances, and personal history of reproductive conditions such as endometrial hyperplasia.

The Impact of Early Detection

Improved Treatment Outcomes: Early detection of ovarian and uterine cancer enables timely initiation of treatment when the disease is localized and potentially curable. Surgical resection of early-stage tumors, combined with adjuvant therapies such as chemotherapy or radiation, can significantly improve long-term survival rates and quality of life for patients.

Enhanced Treatment Options: Early-stage ovarian and uterine cancers are more amenable to less aggressive treatment approaches, such as fertility-sparing surgery or minimally invasive procedures. By detecting these malignancies at an early stage, clinicians can offer patients a broader range of treatment options with fewer associated risks and complications.


In conclusion, early detection through screening plays a critical role in combating ovarian and uterine cancer, offering a lifeline to those at risk of these deadly diseases. By raising awareness of the importance of screening, recognizing common symptoms, and addressing risk factors, we can empower women to take charge of their health and seek timely medical intervention when needed. Together, we can save lives by detecting ovarian and uterine cancer early and improving treatment outcomes for all.